Anti-Human IgM Immunoglobulin(IM373)

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Anti-Human IgM Immunoglobulin(IM373)

CAT:

37-BNUB0373-500

Size:

500 µL

Price:

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For price, please contact [email protected].

Anti-Human IgM Immunoglobulin(IM373)

Description: Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Synonyms: AGM1; IGHM; Constant Region of Heavy Chain of IgM; Ig Mu Chain C Region
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IGHM
Gene ID: 3507
NCBI Gene ID: 510635
UniProt: P01871; P20769
Cellular Locus: Plasma membrane|Secreted (extracellular)
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant full-length heavy chain of human IgM
Target Antigen: Human IgM
Clonality: Monoclonal
Isotype: IgG2b κ
Clone: IM373
Conjugation: Purified, with BSA
Disease: Tumor
Source: Animal
Applications: IHC, FFPE (verified) | WB (verified)
Validated Applications: IHC, FFPE, WB
Field of Research: Cancer, Immunology, Inflammation
Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 50-75 kDa
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Immunohistology formalin-fixed 0.5-1 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Western blotting 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

Complementary Product Range

Our range of products, including Anti-Human IgM Immunoglobulin(IM373), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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Cat	Name
BNUB0373-100	Anti-Human IgM Immunoglobulin(IM373)
BNUB0373-500	Anti-Human IgM Immunoglobulin(IM373)
BNUM0373-50	Anti-Human IgM Immunoglobulin(IM373)
BNC470373-100	Anti-Human IgM Immunoglobulin(IM373), CF647 conjugate
BNC940373-100	Anti-Human IgM Immunoglobulin(IM373), CF594 conjugate
BNC740373-500	Anti-Human IgM Immunoglobulin(IM373), CF740 conjugate
BNC470373-500	Anti-Human IgM Immunoglobulin(IM373), CF647 conjugate
BNC880373-500	Anti-Human IgM Immunoglobulin(IM373), CF488A conjugate
BNC940373-500	Anti-Human IgM Immunoglobulin(IM373), CF594 conjugate
BNCB0373-100	Anti-Human IgM Immunoglobulin(IM373), Biotin conjugate