MIND4

• Description :

  MIND4 is a neuroprotective thiozoline compound that inhibits the deacetylase SIRT2. MIND4 is also an inducer and activator of the nuclear factor NRF2. MIND4 can induce NRF2 activation in neurons and non-neuronal cells and reduce the production of reactive oxygen and nitrogen intermediates[1].

• UNSPSC :

  12352005

• Target :

  Drug Intermediate

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/mind4.html

• Smiles :

  O=[N+]([O-])C1=C2C=CC=NC2=C(C=C1)SC3=NN=C(N3C4=CC=CC=C4)COC5=CC=CC=C5

• Molecular Formula :

  C24H17N5O3S

• Molecular Weight :

  455.49

• References & Citations :

  [1]SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington’s Disease Models

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1639965-26-6]