Recombinant Human EPO-R (C-Fc)

Recombinant Human EPO-R (C-Fc)

• Background: Erythropoietin (Epo), a glycoprotein produced primarily by the kidney, is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.
• Description: Recombinant Human Erythropoietin Receptor is produced by our Mammalian expression system and the target gene encoding Ala25-Pro250 is expressed with a Fc tag at the C-terminus.
• Synonyms: EpoR; EPO-R; Erythropoietin R; erythropoietin receptor; MGC138358
• CAS Number: 9000-83-3
• UniProt: P19235
• Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Molecular Weight: 52 KDa
• Shipping Conditions: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
• Storage Conditions: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.