Anti-IgA Secretory Component(SC05)

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Anti-IgA Secretory Component(SC05)

CAT:

37-BNUB0050-100

Size:

100 µL

Price:

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For price, please contact [email protected].

Anti-IgA Secretory Component(SC05)

Description: This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Synonyms: ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ECM1
Gene ID: 1893
NCBI Gene ID: 81071
UniProt: Q16610
Cellular Locus: Secreted (extracellular)
Host: Mouse
Species Reactivity: Human, Rat
Immunogen: Secretory Component protein isolated from human colostrum
Target Antigen: IgA Secretory Component
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: SC05
Conjugation: Purified, with BSA
Source: Animal
Applications: Functional studies (published) | IHC, FFPE (verified) | WB (published)
Validated Applications: IHC, FFPE, WB, Functional assays
Field of Research: Cancer, Immunology, Inflammation
Positive Control: Stomach, Lung, or breast tumor
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: ~80 kDa
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Immunohistology formalin-fixed 0.5-1 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Infection Immunity (2010)78(11): 4589-4592. (WB) Clin Exp Immunol (2017) 195: 287-301. (functional studies)
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

Complementary Product Range

Our range of products, including Anti-IgA Secretory Component(SC05), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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Cat	Name
BNUM0050-50	Anti-IgA Secretory Component(SC05)
BNUB0050-100	Anti-IgA Secretory Component(SC05)
BNUB0050-500	Anti-IgA Secretory Component(SC05)
BNCB0050-500	Anti-IgA Secretory Component(SC05), Biotin conjugate
BNC740050-500	Anti-IgA Secretory Component(SC05), CF740 conjugate
BNC040050-100	Anti-IgA Secretory Component(SC05), CF405S conjugate
BNC400050-100	Anti-IgA Secretory Component(SC05), CF640R conjugate
BNC680050-100	Anti-IgA Secretory Component(SC05), CF568 conjugate
BNC680050-500	Anti-IgA Secretory Component(SC05), CF568 conjugate
BNC740050-100	Anti-IgA Secretory Component(SC05), CF740 conjugate