Anditixafortide

CAT: 0804-HY-P2218-01Size: 500 µgDry Ice: NoHazardous: No

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CAT#:0804-HY-P2218-01Size:500 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Anditixafortide (Pentixather) is an endoradiotherapeutic vector. Anditixafortide is a CXCR4-targeting peptide derivative[1]. Anditixafortide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

CAS Number

1821136-83-7

UNSPSC

12352209

Target

CXCR; Radionuclide-Drug Conjugates (RDCs)

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anditixafortide.html

Purity

99.27

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@H](N(C([C@H](NC(CNC1=O)=O)CC2=CC(I)=C(C=C2)O)=O)C)CCCNC(C3=CC=C(C=C3)CNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)=O)CCCNC(N)=N)N[C@H]1CC5=CC6=C(C=CC=C6)C=C5

Molecular Formula

C60H79IN14O14

Molecular Weight

1347.26

References & Citations

[1]Nicolas Lepareur, et al. Clinical Advances and Perspectives in Targeted Radionuclide Therapy. Pharmaceutics. 223, 15, 6.|[2]Ken Herrmann, et al. First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease. J Nucl Med. 2016, 57, 2.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

RDC Peptide

Anditixafortide

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