L-Leucine-13C6,15N

• UNSPSC Description:

  L-Leucine-13C6,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

• Target Antigen:

  Endogenous Metabolite; mTOR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease;PI3K/Akt/mTOR

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-leucine-13c6-15n.html

• Purity:

  99.90

• Solubility:

  H2O : 6.25 mg/mL (ultrasonic)

• Smiles:

  [13CH3][13CH]([13CH3])[13CH2][13C@H]([15NH2])[13C](O)=O

• Molecular Weight:

  138.12

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  202406-52-8