Clomipramine (hydrochloride) (Standard)

Clomipramine (hydrochloride) (Standard)

• CAS Number: 17321-77-6
• UNSPSC Description: Clomipramine (hydrochloride) (Standard) is the analytical standard of Clomipramine (hydrochloride). This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].
• Target Antigen: Serotonin Transporter
• Type: Reference Standards
• Related Pathways: Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/clomipramine-hydrochloride-standard.html
• Smiles: CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=C1C=CC=C3.Cl
• Molecular Weight: 351.31
• References & Citations: [1]Yumi Sugimoto, et al. The tricyclic antidepressant Clomipramine increases plasma glucose levels of mice. J Pharmacol Sci. 2003 Sep;93(1):74-9.|[2]Mushtaq Ahmed, et al. Comparative study of the inhibitory effect of antidepressants on cholinesterase activity in Bungarus sindanus (krait) venom, human serum and rat striatum. J Enzyme Inhib Med Chem. 2008 Dec;23(6):912-7.|[3]Federica Cavaliere,The tricyclic antidepressant Clomipramine inhibits neuronal autophagic flux. Sci Rep. 2019 Mar 19;9(1):4881.
• Shipping Conditions: Room temperature