Anti-Estrogen Receptor(ESR1/420)
CAT:
37-BNUM0420-50
Size:
50 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Estrogen Receptor(ESR1/420)
- Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: ESR1
- Gene ID: 2099
- NCBI Gene ID: 208124
- UniProt: P03372
- Cellular Locus: Nucleus
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant human ESR1 protein (aa290-560)
- Target Antigen: Estrogen Receptor
- Clonality: Monoclonal
- Isotype: IgG2a
- Clone: ESR1/420
- Conjugation: Purified, BSA-free
- Disease: Tumor
- Source: Animal
- Field of Research: Cancer, Endocrinology, Nuclear receptors
- Positive Control: MCF-7 Cells or Breast Cancers.
- Concentration: 1 mg/mL
- Buffer: PBS, no BSA, no azide
- Molecular Weight: 67 kDa
- Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
- Shipping Conditions: Room temperature
- Storage Conditions: -35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years