Phytol

• UNSPSC Description:

  Phytol ((E)-Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities[1][2][3].

• Target Antigen:

  Bacterial; Keap1-Nrf2; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/phytol.html

• Purity:

  98.93

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)|Ethanol : 25 mg/mL (ultrasonic)

• Smiles:

  CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(C)=C/CO

• Molecular Weight:

  296.53

• References & Citations:

  [1]de Moraes J, et al. Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical diseaseSchistosomiasis mansoni. PLoS Negl Trop Dis. 2014 Jan 2;8(1):e2617.|[2]Kim EN, et al. Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 Cells. Cells. 2022 Nov 14;11(22):3596.|[3]Usman MA, et al. Phytol suppresses parasitemia and ameliorates anaemia and oxidative brain damage in mice infected with Plasmodium berghei. Exp Parasitol. 2021 May;224:108097.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  150-86-7