Phytol

• Description:

  Phytol ((E) -Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities[1][2][3].

• Product Name Alternative:

  (E) ​-​Phytol

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial; Keap1-Nrf2; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/phytol.html

• Purity:

  99.76

• Solubility:

  DMSO : 125 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)

• Smiles:

  CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(C)=C/CO

• Molecular Formula:

  C20H40O

• Molecular Weight:

  296.53

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]de Moraes J, et al. Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical diseaseSchistosomiasis mansoni. PLoS Negl Trop Dis. 2014 Jan 2;8 (1) :e2617.|[2]Kim EN, et al. Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 Cells. Cells. 2022 Nov 14;11 (22) :3596.|[3]Usman MA, et al. Phytol suppresses parasitemia and ameliorates anaemia and oxidative brain damage in mice infected with Plasmodium berghei. Exp Parasitol. 2021 May;224:108097.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Schistosome

• CAS Number:

  [150-86-7]