20-Hydroxyganoderic Acid G

20-Hydroxyganoderic Acid G

• CAS Number: 400604-12-8
• UNSPSC Description: 20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/20-hydroxyganoderic-acid-g.html
• Solubility: 10 mM in DMSO
• Smiles: CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4([C@H](O)C3=O)C)[C@@](C)(O)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H]
• Molecular Weight: 548.66
• References & Citations: [1]Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported