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Laprafylline

CAT: 0804-HY-106306-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106306-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Laprafylline (S 9795), a xanthine derivative, is a bronchodilator. Laprafylline has potent anti-bronchoconstrictive effects, inhibiting action on mast cell degranulation and phosphodiesterase (PDE) activity (IC50 of 6 μM) [1].
CAS Number
90749-32-9
Product Name Alternative
S 9795
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/laprafylline.html
Solubility
10 mM in DMSO
Smiles
CC(C)CN1C2=C(C(N(C)C1=O)=O)N=C(CCN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)N2
Molecular Formula
C29H36N6O2
Molecular Weight
500.64
References & Citations
[1]G Bianchi, et al. Kinetics and brain uptake of S 9795, a new xanthine derivate, in rats. Eur J Drug Metab Pharmacokinet. 1989 Jul-Sep;14 (3) :201-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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M36186-01Laprafylline

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