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Amisulpride

CAT: 0804-HY-14545-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14545-01Size:100 mg
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Description
Amisulpride ((Rac) -Aramisulpride) is a racemic (50:50) mixture of the R-Amisulpride and S-Amisulpride (HY-126068). Amisulpride is a dopamine D2/D3 receptor antagonist with Ki values of 2.8 and 3.2 nM for human dopamine b>D2 and b>D3, respectively. Amisulpride is a 5-HT7 receptor antagonist with a Ki of 44 nM. Amisulpride can be used in psychiatric research[1][2][3].
CAS Number
71675-85-9
Product Name Alternative
(Rac) -Aramisulpride; (Rac) -Esamisulpride; DAN 2163
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Amisulpride.html
Purity
99.81
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 0.2 mg/mL (ultrasonic)
Smiles
CCN1C(CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1
Molecular Formula
C17H27N3O4S
Molecular Weight
369.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Schoemaker H, et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther. 1997 Jan;280 (1) :83-97.|[2]Pawar GR, et al. Evaluation of antidepressant like property of amisulpride per se and its comparison with fluoxetine and olanzapine using forced swimming test in albino mice. Acta Pol Pharm. 2009 May-Jun;66 (3) :327-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT7 Receptor; D2 Receptor; D3 Receptor

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CatalogName
B1479-100Amisulpride

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