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Creatine Phosphokinase (2ba6), 0.2mg/mL

CAT: 0037-BNUB0196-100Size: 1x 100 µLDry Ice: NoHazardous: No
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CAT#:0037-BNUB0196-100Size:1x 100 µL
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Description
Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments. They provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type) . There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB. It shows minimal reactivity with other human serum proteinsPrimary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
B-CK; BB-CK; creatine kinase-B; Creatine kinase B chain; CKBB creatine kinase B-type; creatine kinase; brain; CKBB; Brain creatine kinase; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Creatine phosphokinase BB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CKB
Gene ID
1152
NCBI Gene ID
173724
UniProt
P12277
Swiss Prot
P12277
Host
Mouse
Species Reactivity
Human
Reactivity
Creatine Phosphokinase
Immunogen
Human CKBB protein
Target Antigen
Creatine Phosphokinase
Clonality
Monoclonal
Clone
2ba6
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Metabolism
Positive Control
Cerebellum
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
43 kDa (Monomer) ; 86 kDa (Dimer)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

UniProtKB · P12277

Creatine kinase B-type

KCRB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12277
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CKB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.3.2
Processing
—
Secondary accessions
A8K236, B2R5R4, Q2LE07, Q6FG40, Q9UC66
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneMitochondrion

PTM

Isopeptide bondNitrationPhosphoproteinUbl conjugation

Molecular function

KinaseTransferase
Product Datasheet
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Alternative Products

CatalogName
APR07315GMonoclonal Creatine Phosphokinase-BB (CK-BB) Antibody - With BSA and Azide, Clone: 2ba6
APR07316GMonoclonal Creatine Phosphokinase-BB (CK-BB) Antibody - Without BSA and Azide, Clone: 2ba6
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397042Creatine Phosphokinase discontinued
C7910-01Creatine Kinase (CK, Creatine Phosphokinase, Creatine N-Phosphotransferase, CPK, Phosphocreatine Phosphokinase)
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