Rovanersen

CAT: 0804-HY-132593-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-132593-01Size:1 mg

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Description

Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research[1].

CAS Number

2072901-32-5

Product Name Alternative

WVE-120101

UNSPSC

12352208

Target

Huntingtin

Type

Oligonucleotides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rovanersen.html

Purity

94.24

Solubility

H2O : ≥ 50 mg/mL

Smiles

[Rovanersen]

Molecular Formula

C202H259N82O111P19S13

Molecular Weight

6617.00

References & Citations

[1]M Meena, et al. Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001) . AAN Enterprises. April 18, 2017; 88 (16 Supplement) .

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

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