Syk-IN-1

Syk-IN-1

• CAS Number: 1491150-77-6
• UNSPSC Description: Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].
• Target Antigen: Syk
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/syk-in-1.html
• Purity: 99.18
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O
• Molecular Weight: 366.42
• References & Citations: [1]Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25(20):4642-4647.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported