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CD98 (IPO-T10), 0.2mg/mL

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CAT#:0037-BNUB0337-100Size:1x 100 µL
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Description
CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
CAS Number
9007-83-4
Synonyms
4F2, 4F2HC, 4T2HC, CD98HC; MDU1; NACAE; Slc3a2; Solute Carrier Family 3 (activators of dibasic and neutral amino acid transport) Member 2, E16, LAT1, MPE16, hLAT1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SLC3A2
Gene ID
6520
NCBI Gene ID
502769
UniProt
P08195
Swiss Prot
P08195
Host
Mouse
Species Reactivity
Human
Reactivity
CD98
Immunogen
Molt 13 T cell line
Target Antigen
CD98
Clonality
Monoclonal
Clone
IPO-T10
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (expected)
Field of Research
Transporters
Positive Control
HL-60, Jurkat, MG63, HUT-78, K562, YT, U937, Hep-G2 cells, Tonsil
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
Heterodimer (125 kDa) made of a disulfide-linked glycosylated heavy chain of approximately 80-90 kDa and a non-glycosylated light chain
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Int Immunol (2000) 12(7), 1051-1061. (Flow, functional studies) Immunology (1999) 96(1): 35-47. (functional studies)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

UniProtKB · P08195

Amino acid transporter heavy chain SLC3A2

4F2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08195
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC3A2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
J3KPF3, Q13543
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Amino-acid transportTransport

Cellular component

Cell junctionCell membraneLysosomeMembrane

Molecular function

Host cell receptor for virus entryReceptor

Domain

Signal-anchorTransmembraneTransmembrane helix
Product Datasheet
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