CD71 (DF1513), 0.2mg/mL

• Description:

  This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV) . This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  TFRC

• Gene ID:

  7037

• NCBI Gene ID:

  529618

• UniProt:

  P02786

• Swiss Prot:

  P02786

• Host:

  Mouse

• Species Reactivity:

  Human

• Reactivity:

  CD71|Transferrin Receptor

• Immunogen:

  KG1 acute myeloid leukemia cell line

• Target Antigen:

  CD71 | Transferrin Receptor

• Clonality:

  Monoclonal

• Clone:

  DF1513

• Type:

  Primary

• Source:

  Animal

• Origin:

  Animal

• Applications:

  Flow (verified) |IF (verified) |WB (verified)

• Field of Research:

  Cancer

• Positive Control:

  CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

• Stability:

  2 years

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight:

  85-95 kDa (monomer) ; 190 kDa (dimer)

• Shipping Conditions:

  RT (ND)

• Storage Conditions:

  Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  Guaranteed for at least 24 months from date of receipt when stored as recommended

• Fragment:

  IgG1, kappa

• Species:

  Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

• Classification:

  PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

• CAS Number:

  9007-83-4

• Conjugate:

  Purified, with BSA