CD71 (DF1513), 0.2mg/mL

• Description :

  This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV) . This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms :

  Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

• UNSPSC :

  41116161

• UNSPSC Description :

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name :

  TFRC

• Gene ID :

  7037

• NCBI Gene ID :

  529618

• UniProt :

  P02786

• Swiss Prot :

  P02786

• Host :

  Mouse

• Species Reactivity :

  Human

• Reactivity :

  CD71|Transferrin Receptor

• Immunogen :

  KG1 acute myeloid leukemia cell line

• Target Antigen :

  CD71 | Transferrin Receptor

• Clonality :

  Monoclonal

• Clone :

  DF1513

• Type :

  Primary

• Source :

  Animal

• Origin :

  Animal

• Applications :

  Flow (verified) |IF (verified) |WB (verified)

• Field of Research :

  Cancer

• Positive Control :

  CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

• Stability :

  2 years

• Concentration :

  0.2 mg/mL

• Buffer :

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight :

  85-95 kDa (monomer) ; 190 kDa (dimer)

• Shipping Conditions :

  RT (ND)

• Storage Conditions :

  Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life :

  Guaranteed for at least 24 months from date of receipt when stored as recommended

• Fragment :

  IgG1, kappa

• Species :

  Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

• Classification :

  PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

• CAS Number :

  9007-83-4

• Conjugate :

  Purified, with BSA