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PEG6- (CH2CO2H) 2

CAT: 0804-HY-122702-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122702-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PEG6- (CH2CO2H) 2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].
CAS Number
77855-76-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/peg6-ch2co2h-2.html
Purity
95.0
Solubility
Ethanol : 100 mg/mL (ultrasonic)
Smiles
O=C(O)COCCOCCOCCOCCOCCOCC(O)=O
Molecular Formula
C14H26O10
Molecular Weight
354.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8 (1) :830.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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