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VEC6

CAT: 0804-HY-28099Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-28099Size:1 Each
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Description
VEC6 (NSC 11435) is an inhibitor of VEZF1–DNA interaction and has the activity to recapitulate RhoB loss in ischemic retinopathy. VEC6 reduces pathological angiogenesis and promotes lymphangiogenesis. VEC6 plays a unique role in angiogenesis and lymphangiogenesis by regulating the expression of different sets of genes in endothelial cells. VEC6 has an inhibitory effect on VEZF1-mediated transcriptional activity, thereby affecting the proliferation and sprouting of endothelial cells[1].
CAS Number
3431-16-1
Product Name Alternative
NSC 11435
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vec6.html
Smiles
CN(C(CCC1)C2)C1CN2/N=N/C3=CC=CC=C3
Molecular Formula
C14H20N4
Molecular Weight
244.34
References & Citations
[1]RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5776043VEC6

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