IU1

• UNSPSC Description:

  IU1 is a special Usp14 inhibitor with an IC50 of 4-5 μM.

• Target Antigen:

  Autophagy; Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Cell Cycle/DNA Damage

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/IU1.html

• Smiles:

  CC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3

• Molecular Weight:

  300.37

• References & Citations:

  [1]Lee BH, et al. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 2010 Sep 9;467(7312):179-84.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  314245-33-5