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Sipatrigine

CAT: 0804-HY-108335-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108335-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke[1][2].
CAS Number
130800-90-7
Product Name Alternative
619C89; BW 619C89
UNSPSC
12352005
Target
Calcium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sipatrigine.html
Concentration
10mM
Purity
99.63
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
NC1=NC(N2CCN(C)CC2)=NC=C1C3=CC(Cl)=CC(Cl)=C3Cl
Molecular Formula
C15H16Cl3N5
Molecular Weight
372.68
References & Citations
[1]Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24 (7) :1063-7.|[2]Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
530006Sipatrigine
A12943-200Sipatrigine 200mg
A12943-50Sipatrigine 50mg
A12943-25Sipatrigine 25mg
A12943-100Sipatrigine 100mg
A12943-10Sipatrigine 10mg
A12943-5Sipatrigine 5mg
A12943-1Sipatrigine 1mg
A12943-10mM-DSipatrigine 10mM * 1mL in DMSO

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