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Ipsapirone

CAT: 0804-HY-19686-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19686-01Size:5 mg
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Description
Ipsapirone (TVX Q 7821) is an anxiolytic compound and a 5-HT1A receptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits 5-HT1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT2 and the α1-adrenergic function[1][2].
CAS Number
95847-70-4
Product Name Alternative
TVX Q 7821 (free base)
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ipsapirone.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C2C=CC=C1)N(CCCCN3CCN(C4=NC=CC=N4)CC3)S2(=O)=O
Molecular Formula
C19H23N5O3S
Molecular Weight
401.49
References & Citations
[1]J Maj, et al. Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions. J Neural Transm. 1987;70 (1-2) :1-17.|[2]Stephen M. Stahl, et al. Effectiveness of ipsapirone, a 5-HT-1A partial agonist, in major depressive disorder: support for the role of 5-HT-1A receptors in the mechanism of action of serotonergic antidepressants. Int J Neuropsychopharmacol. 1998 Jul;1 (1) :11-18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3

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T27623-01Ipsapirone hydrochloride

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