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CD3e (B-B12), 0.2mg/mL

CAT: 0037-BNUB1052-500Size: 1x 500 µLDry Ice: NoHazardous: No
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CAT#:0037-BNUB1052-500Size:1x 500 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Reacts with five invariable CD3 chains (designated as and) with molecular weight ranging from 16-28 kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD 3E|CD3 epsilon|CD3 TCR complex|CD3E|CD3e antigen epsilon polypeptide (TiT3 complex) |T cell antigen receptor complex epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain|T3E|TCRE|TiT3 complex
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD3E
Gene ID
916
NCBI Gene ID
3003
UniProt
P07766
Swiss Prot
P07766
Host
Mouse
Species Reactivity
Human
Reactivity
CD3e
Immunogen
Human T cell leukemia cells
Target Antigen
CD3e
Clonality
Monoclonal
Clone
B-B12
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (verified) |IF (verified)
Field of Research
Immunology
Positive Control
Jurkat cells. Tonsil and lymph node
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
20 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Kishimoto T. et al. eds. Leukocyte Typing VI, p44-48 and p1111, Garland Publishing, Inc, New York and London, 1997.
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
Product Datasheet
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