Anti-CD38(AT1)

• Description:

  CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells)._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_

• Synonyms:

  Cell differentiation antigen 37; GP52 40; Tetraspanin-26; Tspan-26; TSPAN26

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  CD38

• Gene ID:

  951

• NCBI Gene ID:

  479214

• UniProt:

  P28907

• Cellular Locus:

  Plasma membrane

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  human T cell line CCRF-CEM

• Target Antigen:

  CD38

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  AT1

• Conjugation:

  Purified, BSA-free

• Source:

  Animal

• Applications:

  Flow, surface (published) | IF (published) | IHC, FFPE (published) | IP (published) | WB (published)

• Validated Applications:

  FC, IF, IHC, FFPE, IP, WB

• Field of Research:

  Immunology

• Positive Control:

  CCRF-CEM cells, Tonsil, Spleen or Skin

• Concentration:

  1 mg/mL

• Buffer:

  PBS, no BSA, no azide

• Molecular Weight:

  ~45 kDa (Glycoprotein); 35 kDa (protein core)

• References & Citations:

  Note: References for this clone sold by other suppliers may be listed for expected applications. Diabetologia (2002) 45:1667-1677. (IHC, FFPE; IF) BMC Immunol (2004) 5: 21. (Flow, IF, WB) J Cellular Biochem (2008) 103:1294-1308. (IP, WB, Flow, IF)

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  -35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4