(S,R,S)-AHPC-PEG2-C5-N3

(S,R,S)-AHPC-PEG2-C5-N3

• UNSPSC Description: (S,R,S)-AHPC-PEG2-C5-N3 is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-C5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-peg2-c5-n3.html
• Smiles: O=C([C@@H]1C[C@@H](O)CN1C([C@H](C(C)(C)C)NC(COCCOCCNC(CCCCCN=[N+]=[N-])=O)=O)=O)NCC2=CC=C(C3=C(C)N=CS3)C=C2
• Molecular Weight: 714.88
• References & Citations: [1]Yang B, et al. Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3. Bioorg Med Chem Lett. 2024 Nov 1;112:129945.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported