(S,R,S)-AHPC-PEG2-C5-N3

• UNSPSC Description:

  (S,R,S)-AHPC-PEG2-C5-N3 is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-C5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/s-r-s-ahpc-peg2-c5-n3.html

• Smiles:

  O=C([C@@H]1C[C@@H](O)CN1C([C@H](C(C)(C)C)NC(COCCOCCNC(CCCCCN=[N+]=[N-])=O)=O)=O)NCC2=CC=C(C3=C(C)N=CS3)C=C2

• Molecular Weight:

  714.88

• References & Citations:

  [1]Yang B, et al. Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3. Bioorg Med Chem Lett. 2024 Nov 1;112:129945.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported