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Elab Fluor® 700 Anti-Human CD55 Antibody[HI55a]

CAT: 0763-AN00336M1-01Size: 20 TestsDry Ice: NoHazardous: No
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CAT#:0763-AN00336M1-01Size:20 Tests
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Background
CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI) -anchored single chain glycoprotein also known as decay-accelerating factor (DAF) . It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.
Abbreviation
CD55
Gene ID
1604
UniProt
P13591
Host
Mouse
Reactivity
Human
Target
Complement decay-accelerating factor; CD55; CR; DAF
Clonality
Monoclonal
Clone
HI55a
Conjugation
Elab Fluor®700
Applications
FCM
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ

UniProtKB · P13591

Neural cell adhesion molecule 1

NCAM1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13591
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NCAM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
N-CAM-1, NCAM-1
EC number
—
Processing
Precursor
Secondary accessions
A8K8T8, P13592, P13593, Q05C58, Q15829, Q16180, Q16209, Q59FL7, Q86X47, Q96CJ3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinGPI-anchorLipoproteinPhosphoprotein

Molecular function

Host cell receptor for virus entryReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix