Anti-CD28(CB28)

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MSDS

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Anti-CD28(CB28)

CAT:

37-BNUB0384-100

Size:

100 µL

Price:

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For price, please contact [email protected].

Anti-CD28(CB28)

Description: Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Synonyms: T-cell-specific surface glycoprotein CD28; Tp44
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD28
Gene ID: 940
NCBI Gene ID: 591629
UniProt: P10747
Cellular Locus: Plasma membrane
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant human CD28 protein
Target Antigen: CD28
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: CB28
Conjugation: Purified, with BSA
Source: Animal
Applications: Flow (verified) | IF (verified)
Validated Applications: FC, IF
Field of Research: Immunology
Positive Control: Jurkat cells or human lymph nodes and tonsils.
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 44 kDa (monomer); 88 kDa (dimer)
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

Complementary Product Range

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Find us on

Cat	Name
BNUB0384-100	Anti-CD28(CB28)
BNUB0384-500	Anti-CD28(CB28)
BNUM0384-50	Anti-CD28(CB28)
BNC740384-100	Anti-CD28(CB28), CF740 conjugate
BNC400384-100	Anti-CD28(CB28), CF640R conjugate
BNC880384-500	Anti-CD28(CB28), CF488A conjugate
BNC940384-500	Anti-CD28(CB28), CF594 conjugate
BNCB0384-100	Anti-CD28(CB28), Biotin conjugate
BNC740384-500	Anti-CD28(CB28), CF740 conjugate
BNC040384-500	Anti-CD28(CB28), CF405S conjugate