Coronalolide

• Description :

  Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively[1].

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/coronalolide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(CC[C@@]12[C@]3([C@](C[C@](O4)([H])[C@@]2([H])C(C4=O)=C)([H])[C@]5([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC5)CC3)C)C1)=O

• Molecular Formula :

  C30H42O5

• Molecular Weight :

  482.65

• References & Citations :

  [1]Thanesuan Nuanyai, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from Gardenia sootepensis. J Nat Prod. 2009 Jun;72 (6) :1161-4.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [268214-51-3]