Anti-IL-4 (Interleukin-4), Mouse(11B11), CF740 conjugate

• Description:

  IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  B cell growth factor 1 (BCGF1); B cell IgG differentiation factor; B-Cell Stimulatory Factor 1 (BSF1); Binetrakin; IGG1 induction factor; IL4; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra

• CAS Number:

  9007-83-4

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene ID:

  16189

• NCBI Gene ID:

  276360

• UniProt:

  P07750

• Cellular Locus:

  Secreted (extracellular)

• Host:

  Rat

• Species Reactivity:

  Mouse

• Immunogen:

  Partially Purified native Mouse IL-4

• Target Antigen:

  IL-4 ,

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  11B11

• Conjugation:

  CF740

• Source:

  Animal

• Applications:

  Flow, intracellular (published) | Functional studies (published) | ELISA (published)

• Validated Applications:

  FC, ELISA

• Positive Control:

  Spleen, Thymus or Lymph Node.

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% rBSA, 0.05% azide

• Molecular Weight:

  13-14 kDa

• References & Citations:

  Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1992) 89:6065-6069. (functional studies; ELISA) J Immunol (2005) 174:1063-1072. (ELISA, Flow)

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years