Fluorescein Di-β-D-Glucuronide

Fluorescein Di-β-D-Glucuronide

• CAS Number: 134869-04-8
• UNSPSC Description: Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies[1].
• Target Antigen: Bacterial
• Type: Dye Reagents
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/fluorescein-di-β-d-glucuronide.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC2(C3=CC=C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C3OC5=CC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=CC=C52)C7=CC=CC=C71
• Molecular Weight: 684.55
• References & Citations: [1]Michael Chen, et al. Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe. Sci Rep. 2017 Jun 9;7(1):3142.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported