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NF023

CAT: 0804-HY-167704Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-167704Size:1 Each
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Description
NF023 is a compound that inhibits X-BIR1/TAB1 assembly activity. NF023 can affect cell survival signaling pathways by interfering with XIAP-mediated NF-κB activation. NF023 also shows potential as a selective P2X1 adenylate receptor antagonist. This compound has the potential to synergize with existing pro-apoptotic drugs and play an important role in cancer suppression[1].
CAS Number
99777-90-9
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nf023.html
Smiles
O=C(NC1=CC=CC(C(NC2=CC=C(S(=O)(O)=O)C3=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C23)=O)=C1)NC4=CC=CC(C(NC5=CC=C(S(=O)(O)=O)C6=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C56)=O)=C4
Molecular Formula
C35H26N4O21S6
Molecular Weight
1030.99
References & Citations
[1]NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
TP2272-01NF023 hexasodium

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