NF023

• Description:

  NF023 is a compound that inhibits X-BIR1/TAB1 assembly activity. NF023 can affect cell survival signaling pathways by interfering with XIAP-mediated NF-κB activation. NF023 also shows potential as a selective P2X1 adenylate receptor antagonist. This compound has the potential to synergize with existing pro-apoptotic drugs and play an important role in cancer suppression[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nf023.html

• Smiles:

  O=C(NC1=CC=CC(C(NC2=CC=C(S(=O)(O)=O)C3=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C23)=O)=C1)NC4=CC=CC(C(NC5=CC=C(S(=O)(O)=O)C6=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C56)=O)=C4

• Molecular Formula:

  C35H26N4O21S6

• Molecular Weight:

  1030.99

• References & Citations:

  [1]NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [99777-90-9]