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CD147 (BSG/963), 1mg/mL

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Description
This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
5A11 Antigen; 5F7; Basigin; Blood brain barrier HT7 antigen BSG; Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) ; Leukocyte Activation Antigen M6; Neurothelin; OK Blood Group Antigen; TCSF; Tumor Cell-derived Collagenase Stimulatory Factor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BSG
Gene ID
682
NCBI Gene ID
501293
UniProt
P35613
Swiss Prot
P35613
Host
Mouse
Species Reactivity
Human
Reactivity
CD147
Immunogen
Recombinant human BSG protein
Target Antigen
CD147
Clonality
Monoclonal
Clone
BSG/963
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology
Positive Control
HSB2 cells. Renal Cell, Colon or Testicular carcinoma
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
35 kDa (non-reduced) ; 40 kDa (reduced)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

UniProtKB · P35613

Basigin

BASI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35613
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BSG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A6NJW1, D3YLG5, Q7Z796, Q8IZL7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Biological process

AngiogenesisHost-virus interaction

Molecular function

Blood group antigenHost cell receptor for virus entryReceptor

Cellular component

Cell membraneCell projectionEndoplasmic reticulumEndosomeMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Ligand

LectinMannose-binding
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