Retelliptine

CAT: 0804-HY-106307Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-106307Size:1 Each

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Description

Retelliptine (BD84), a derivative of ellipticine, is an inhibitor of Topoisomerase II with anticancer activity. Retelliptine can bind to DNA and inhibit Topoisomerase II during DNA replication[1][2].

CAS Number

72238-02-9

Product Name Alternative

BD84

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/retelliptine.html

Smiles

CCN(CC)CCCNC1=NC=CC2=C(C)C3=C(C4=CC(OC)=CC=C4N3)C(C)=C21

Molecular Formula

C25H32N4O

Molecular Weight

404.55

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]Kattan J, et al. Phase I study of retelliptine dihydrochloride (SR 95325 B) using a single two-hour intravenous infusion schedule[J]. American journal of clinical oncology, 1994, 17 (3) : 242-245.|[2]Maulard C, et al. Binding of retelliptine, a new antitumoral agent, to serum proteins and erythrocytes[J]. Biochemical pharmacology, 1990, 40 (4) : 895-898.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

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