Gentamicin (sulfate)
CAT:
804-HY-A0276-02
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Gentamicin (sulfate)
- CAS Number: 1405-41-0
- UNSPSC Description: Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM[1][2][3][4].
- Target Antigen: Antibiotic; Bacterial
- Type: Natural Products
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection; Cancer
- Assay Protocol: https://www.medchemexpress.com/Gentamicin__sulfate_.html
- Solubility: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : ≥ 30 mg/mL
- Smiles: O=S(O)(O)=O.O[C@]1(C)C(NC)[C@@H](O)[C@@H](O[C@H]2C(N)C[C@H](N)[C@@H](O[C@@H]3[C@H](N)CC[C@@H]([R])O3)[C@@H]2O)OC1.NC[*].C[C@H]([*])N.C[C@H]([*])NC.[R=].[or].[or]
- Molecular Weight: 561.65 (Average)
- References & Citations: [1]Xu W, et al. A rapid and sensitive method for kinetic study and activity assay of DNase I in vitro based on a GO-quenched hairpin probe. Anal Bioanal Chem. 2016 May;408(14):3801-9.|[2]Rudin A, et al. Antibacterial activity of gentamicin sulfate in tissue culture. Appl Microbiol. 1970 Dec;20(6):989-90.|[3]Kumar CG, et al. Microbial biosynthesis and applications of gentamicin: a critical appraisal.|[4]Espersen F, et al. Effect of treatment with methicillin and gentamicin in a new experimental mouse model of foreignbody infection. Antimicrob Agents Chemother. 1994 Sep;38(9):2047-53.ACS Appl Mater Interfaces. 2019 Oct 16;11(41):38190-38204. |ACS Infect Dis. 2024 Apr 12;10(4):1327-1338.|Am J Physiol Cell Physiol. 2019 Aug 1;317(2):C277-C286.|Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702.|Aquaculture. 2021, 736248.|Cell Death Dis. 2023 Jan 11;14(1):15.|Cell Host Microbe. 2024 Jul 23:S1931-3128(24)00254-3.|Cell Transplant. Jan-Dec 2021;30:963689721997151.|Evid Based Complement Alternat Med. 2015;2015:639412.|Immun Inflamm Dis. 2024 Jul;12(7):e1149.|Int J Biol Sci. 2024 Oct 7;20(14):5415-5435.|J Ethnopharmacol. 2020 Sep 15;259:112882. |Mol Immunol. 2017 Dec;92:151-160.|Mol Med Rep. 2016 Dec;14(6):5304-5310.|Mutat Res Genet Toxicol Environ Mutagen. 2023 Apr 5,503636.|Nat Commun. 2022 Mar 2;13(1):1116.|Research Square Print. October 6th, 2022.|Toxicology. 2022 Nov 29;483:153386.|Biomed Pharmacother. 2023 Nov 8:115856.|bioRxiv. 2024 May 10.|Cell. 2024 Feb 15;187(4):882-896.e17|Chin J Traumatol. 2024 Jul 3:S1008-1275(24)00075-0.|Curr Microbiol. 2023 May 31;80(7):230.|Emerg Microbes Infect. 2024 Dec;13(1):2321981.|Food Chem. 2022 Sep 26;403:134399.|Int J Med Microbiol. 2023 Mar 28;313(2):151578.|Microorganisms. 2024 Mar 13, 12(3), 575.|Nat Microbiol. 2023 Mar;8(3):410-423.|Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct 1.|Vet Microbiol. 2024 May, 292, 110046.|Vet Res Commun. 2024 Sep 26.|Virulence. 2024 Oct 10:2415952.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched