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MDVN1003

CAT: 0804-HY-101798Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101798Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MDVN1003 is a Bruton's tyrosine kinase (BTK) and phosphatidylinositol-3-kinase delta (PI3Kδ) dual inhibitor which prevents the activation of B cells and inhibits the phosphorylation of protein kinase B (AKT) and extracellular signal-regulated kinase 1/2 (ERK 1/2) . MDVN1003 can be used for non-Hodgkin’s lymphoma (NHL) research[1].
CAS Number
2058116-52-0
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdvn1003.html
Smiles
NC1=C2C(N(C3CC(C=CC(N)=C4)=C4C3)N=C2C5=CC(NCCO6)=C6C(F)=C5)=NC=N1
Molecular Formula
C22H20FN7O
Molecular Weight
417.44
References & Citations
[1]Alfaro J, et al. Dual Inhibition of Bruton's Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin's B Cell Malignancies. J Pharmacol Exp Ther. 2017 May;361 (2) :312-321.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19153945-01MDVN1003

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