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Teneliximab

CAT: 0804-HY-P99321-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99321-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].
CAS Number
299423-37-3
Product Name Alternative
BMS 224819; Chi220; Anti-Human CD40 Recombinant Antibody
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/teneliximab.html
Purity
99.0
Solubility
10 mM in H2O
Smiles
[Teneliximab]
Molecular Weight
(146.06 kDa)
References & Citations
[1]Maria A Argiriadi, et al. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol. 2019 Aug 5;20 (1) :29.|[2]Andrew B Adams, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol. 2005 Jan 1;174 (1) :542-50.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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