Fentiazac

CAT: 0804-HY-118752-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-118752-01Size:5 mg

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Description

Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis[1][2][3].

CAS Number

18046-21-4

Product Name Alternative

PX-112, ABR-215757-d5-1; ABR 25757-d5-1, trans-PX-102, (-)-PX-102 (trans isomer); (-)-PX-104

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fentiazac.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC1=C(N=C(S1)C2=CC=CC=C2)C3=CC=C(C=C3)Cl)O

Molecular Formula

C17H12ClNO2S

Molecular Weight

329.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Emilio Marmo, et al. Experimental and clinical pharmacology of fentiazac, a new, non-steroidal anti-inflammatory agent. Current Medical Research and Opinion.Volume 6, 1979 - Issue sup2.|[2]Gabor Katona, et al. Efficacy and tolerability of fentiazac in rheumatoid arthritis: Double-blind study versus indomethacin. Current Medical Research and Opinion. Volume 6, 1979 - Issue sup2.|[3]Famaey JP, Gaci O, Ginsberg F. Fentiazac in the treatment of osteoarthritis and tendinitis. Curr Med Res Opin. 1983;8 (9) :675-81.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

Fentiazac

2-[4-(4-chlorophenyl)-2-phenyl-5-thiazolyl]acetic acid is a member of thiazoles.

CAS Number	18046-21-4
PubChem CID	28871
IUPAC Name	2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid
Molecular Formula	C17H12ClNO2S
Molecular Weight	329.8
XLogP	5.2
Topological Polar Surface Area	78.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Heavy Atom Count	22
Formal Charge	0
Complexity	381

SMILES

C1=CC=C(C=C1)C2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)Cl

InChI

InChI=1S/C17H12ClNO2S/c18-13-8-6-11(7-9-13)16-14(10-15(20)21)22-17(19-16)12-4-2-1-3-5-12/h1-9H,10H2,(H,20,21)

InChIKey

JIEKMACRVQTPRC-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 18046-21-4

CID: 28871

Formula: C17H12ClNO2S

MW: 329.8

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	329.8
XLogP3	5.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	329.0277275
Monoisotopic Mass	329.0277275
Topological Polar Surface Area	78.4 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	381
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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BUP00999-01	Fentiazac

Fentiazac

Chemical Information

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