Fumaric acid-13C2,d2

Fumaric acid-13C2,d2

• CAS Number: 100858-52-4
• UNSPSC Description: Fumaric acid-13C2,d2 is the deuterium and 13C labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: O[13C](/C([2H])=C([2H])/[13C](O)=O)=O
• Molecular Weight: 120.07
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported