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DBIBB

CAT: 0804-HY-117779-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117779-01Size:5 mg
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Description
DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2) . DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system[1].
CAS Number
1569309-92-7
Product Name Alternative
5-(4-Phenoxybutoxy)psoralen, ZM-211975, ZK-76614
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/dbibb.html
Concentration
10mM
Purity
98.07
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1CCCCNS(C2=C(C=CC=C2)C(O)=O)(=O)=O)C3=C4C(C=CC=C4C1=O)=CC=C3
Molecular Formula
C23H20N2O6S
Molecular Weight
452.48
References & Citations
[1]Patil R, et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chem Biol. 2015;22 (2) :206-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
562532DBIBB

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