Riluzole

• Description:

  Riluzole is a benzothiazole derivative which inhibits glutamatergic neurotransmission and blocks voltage-dependent sodium channels (ED₅₀ = 2.3 μM). It reduces the uptake of GABA from neuronal synapse. Riluzole suppresses glutamate-induced seizures in rats with an ED₅₀ value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals with an ED₅₀ value of 4 mg/kg. It is used for the treatment of amyotrophic lateral sclerosis.

• Shipping Conditions:

  RT

• Storage Conditions:

  -20ºC

• Shelf Life:

  36months