Anti-CD100 (Semaphorin-4D)(A8), Biotin conjugate
CAT:
37-BNCB0218-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD100 (Semaphorin-4D)(A8), Biotin conjugate
- Description: CD100 (also known as Semaphorin 4D), is a homodimeric protein comprised of 50 kDa subunits. It is expressed on resting T cells and weakly on other lymphocytes, and its expression is increased on B and T cells after stimulation. CD100 is a cell surface receptor that binds to CD72, Plexin B1 and Plexin B2. It promotes B cell aggregation, cell survival, and cell proliferation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: CD100; Semaphorin-4D; SEMA4D
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: SEMA4D
- Gene ID: 10507
- NCBI Gene ID: 494406
- UniProt: Q92854
- Cellular Locus: Plasma membrane
- Host: Mouse
- Species Reactivity: Human, Monkey, Mouse
- Immunogen: PHA stimulated human peripheral blood lymphocytes.
- Target Antigen: CD100 | Semaphorin-4D
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: A8
- Conjugation: Biotin
- Source: Animal
- Applications: Flow, surface (published) | ELISA (published) | WB (published)
- Validated Applications: FC, ELISA, WB
- Field of Research: Immunology, Neuroscience, Signal transduction
- Positive Control: Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 50 kDa (Monomer)
- Additionnal Information: Functional studies: Order Ab without azide; Flow cytometry: 0.5-1 ug/million cells; Immunofluorescence: 0.5-1 ug/mL; Optimal dilution for a specific application should be determined.
- References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1996) 93:11780-11785. (Flow) PLoS One (2007) 2(9):e818. (Flow, WB, ELISA)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years