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CD100 (Semaphorin-4D) (A8), 1mg/mL

CAT: 0037-BNUM0218-50Size: 1x 50 µLDry Ice: NoHazardous: No
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CAT#:0037-BNUM0218-50Size:1x 50 µL
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Description
CD100 (also known as Semaphorin 4D), is a homodimeric protein comprised of 50 kDa subunits. It is expressed on resting T cells and weakly on other lymphocytes, and its expression is increased on B and T cells after stimulation. CD100 is a cell surface receptor that binds to CD72, Plexin B1 and Plexin B2. It promotes B cell aggregation, cell survival, and cell proliferation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD100; Semaphorin-4D; SEMA4D
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SEMA4D
Gene ID
10507
NCBI Gene ID
494406
UniProt
Q92854
Swiss Prot
Q92854
Host
Mouse
Species Reactivity
Human, Monkey, Mouse
Reactivity
CD100|Semaphorin-4D
Immunogen
PHA stimulated human peripheral blood lymphocytes.
Target Antigen
CD100 | Semaphorin-4D
Clonality
Monoclonal
Clone
A8
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |ELISA (published) |WB (published)
Field of Research
Immunology, Neuroscience, Signal transduction
Positive Control
Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
50 kDa (Monomer)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1996) 93:11780-11785. (Flow) PLoS One (2007) 2(9):e818. (Flow, WB, ELISA)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

UniProtKB · Q92854

Semaphorin-4D

SEM4D_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92854
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SEMA4D
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RPM6, Q7Z5S4, Q8N8B0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Molecular function

Developmental proteinReceptor

Biological process

DifferentiationNeurogenesis

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix
Product Datasheet
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