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JPD447

CAT: 0804-HY-139628-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139628-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
CAS Number
2883235-86-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/jpd447.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
FC(C=C1)=CC=C1C2=C3N(N=C2)C(N4CCCCCC4)=CC(CC)=N3
Molecular Formula
C20H23FN4
Molecular Weight
338.42
References & Citations
[1]Workman SD, et al. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 23;64 (18) :13540-13550.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19221465-01JPD447

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