Propargyl-PEG5-amine

• UNSPSC Description:

  Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/propargyl-peg5-amine.html

• Purity:

  98.86

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C#CCOCCOCCOCCOCCOCCN

• Molecular Weight:

  275.34

• References & Citations:

  [1]Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1589522-46-2