Propargyl-PEG5-Br

• Description:

  Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/propargyl-peg5-br.html

• Purity:

  96.57

• Solubility:

  10 mM in DMSO

• Smiles:

  C#CCOCCOCCOCCOCCOCCBr

• Molecular Formula:

  C13H23BrO5

• Molecular Weight:

  339.22

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1009.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  [1287660-83-6]