Indirubin Derivative E804
CAT:
804-HY-18785-03
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Indirubin Derivative E804
- CAS Number: 854171-35-0
- UNSPSC Description: Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.
- Target Antigen: IGF-1R
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/Indirubin_Derivative_E804.html
- Purity: 98.54
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C/3=N/OCCC(O)CO
- Molecular Weight: 365.38
- References & Citations: [1]Cheng X, et al. Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported