Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP)

Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP)

• Background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
• Description: Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP) (CG1-H52P6) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Asn 461 (CGRPR) & Cys 27 - Val 148 (RAMP1) (Accession # Q16602-1 (CGRPR) & O60894-1 (RAMP1)).
• Specifications: This protein .
• Expression Region: Glu 23 - Asn 461 (CGRPR) & Cys 27 - Val 148 (RAMP1)
• Host: HEK 293
• Target: CGRPR & RAMP1
• Conjugation: Unconjugated
• Source: Human
• Stability: The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.
• Endotoxin: 1.0 EU per μg
• Bioactivity: Immobilized Human CGRPR&RAMP1 Full Length Heterodimer Protein (VLP) (Cat. No. CG1-H52P6) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CGRPR antibody, human IgG with a linear range of 0.5-8 ng/mL (QC tested).
• Format: Liquid
• Buffer: PBS, Arginine, pH7.4
• Additives: Trehalose
• Shipping Conditions: Dry ice
• Storage Conditions: -70°C