tert-Butyl 11-aminoundecanoate
CAT:
804-HY-130715-03
Size:
250 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
tert-Butyl 11-aminoundecanoate
- CAS Number: 220851-29-6
- UNSPSC Description: tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tert-butyl-11-aminoundecanoate.html
- Purity: 99.39
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(OC(C)(C)C)CCCCCCCCCCN
- Molecular Weight: 257.41
- References & Citations: [1]Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported