Biotinylated Anti-SN38 Antibody, Mouse IgG1, Avitag™

• Background:

  The 7-ethyl-10-hydroxycamptothecin (SN-38) is a topoisomerase I inhibitor (chemotherapeutic agent) used in cancer therapy. In a comparative study of SN-38 with a potent chemotherapeutic prodrug, irinotecan (CPT-11), SN-38 was found to be 1000-fold more cytotoxic against colorectal cancer cells as compared to irinotecan.

• Description:

  The 7-ethyl-10-hydroxycamptothecin (SN-38) is a topoisomerase I inhibitor (chemotherapeutic agent) used in cancer therapy. In a comparative study of SN-38 with a potent chemotherapeutic prodrug, irinotecan (CPT-11), SN-38 was found to be 1000-fold more cytotoxic against colorectal cancer cells as compared to irinotecan.

• Host:

  HEK293

• Origin Species:

  Mouse

• Target:

  SN38

• Conjugation:

  Biotin-labeled

• Tag:

  Mouse IgG1 & C-Avi | Mouse Kappa

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

• Purity:

  90%

• Bioactivity:

  Immobilized Sacituzumab Govitecam at 1 μg/mL (100 μL/well) can bind Biotinylated Anti-SN38 Antibody, Mouse IgG1, Avitag (Cat. No. SN8-BVM808) with a linear range of 0.1-8 ng/mL (Routinely tested).

• Format:

  Powder

• Buffer:

  PBS, pH7.5

• Additives:

  Trehalose

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  25ug*1

• Species:

  Mouse

• CAS Number:

  9007-83-4